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The crude drug extracts caused transient hypotensive effect which is partly inhibited by atropine. The gluco alkaloid, saponin and resin fraction increased the force of contraction of isolated frog's heart and caused gradual rise in blood pressure levels. The alcoholic leaf extract, resinous and crystalline fi-acons caused contraction of dog tracheal chain while the glucoalkaloid and alcoholic stem extract after initial potentiation caused refractoriness to the constrictor responses of acetylcholine and histamine. Histamine releasing effects have been shown.
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Roots are one of the constituents of Dasamulasava. The plant is useful in fever, cough, asthma, constipation. Seeds are used as diuretic. The juice of the berries is reported to he useful in sore throat. A decoction of plant is used in gonorrhoea and it also said to promote conception in females. A. clinical trial showed kantakari to be useful in cases of Kasa Roga (cough) and also in Tamakswasa (bronchial asthma). The plant has a definite effect in diminishing the intensity of cough and dyspnoea.
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